Organe concerné : Voies biliaires
Ligne de traitement : Localement avancé | 1ère ligne M+
Sous-type tumoral :
Thérapie d’entretien ciblée versus traitement standard dans le cancer biliaire avancé : un essai de phase 3 international, randomisé, contrôlé, en ouvert
The object of this trial is to evaluate whether the introduction of a targeted therapy after 4 cycles of the current standard-of-care treatment for advanced biliary cancer is superior to continuing with the standard treatment.
The trial is composed of two phases: (i) An initial screening phase to identify a suitable patient population, during which a molecular profile of the patient's tumour will be obtained, and (ii) a randomised comparative trial in which patients with disease control after 4 cycles of standard treatment, and whose tumour harbours a targetable molecular alteration, will be randomised (2:1) to receive either a matched targeted therapy or to continue with the standard treatment.
CHU Limoges :
Lynda Pervieux : 05 55 08 72 92 ou lynda.pervieux@chu-limoges.fr
CHU de BORDEAUX:
amandine.mourthe@chu-bordeaux.fr / camille.ducerf@chu-bordeaux.fr